Disease of the Suprarenal Capsules, or Pernicious Anæmia

goes on cheerfully attending to his business, when, perhaps, only symptoms of acid dyspepsia exist. The patient now complains of slight vertigo, languor and lassitude, loathsomeness in doing his daily work. His appetite fails, his heart burns, and he feels sick after food. There may be slight diarrhoea towards morning. His eyes become nearly white ; pigmentary changes become distinctly visible over the eye-lids and the orbits, and his general complexion becomes darker than usual. In some cases I have seen the temperature at this stage of illness go slightly above normal; the patient feels dejected in spirits, he spits up constantly and brings up his food ; his pulse becomes quick aud feeble ; sometimes an anajmic murmur is heard over the